Title : Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism.

Pub. Date : 2017 Oct 3

PMID : 28923935






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Our results suggest that the repressive activity of RXR on prometastatic genes is mediated primarily through direct DNA binding of the receptor along with nuclear receptor corepressor (NCoR) and silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressors and is largely unresponsive to ligand activation. Tretinoin retinoid X receptor alpha Homo sapiens