Title : A comparison of the inhibitory effects of roxatidine acetate hydrochloride and cimetidine on cytochrome P-450-mediated drug-metabolism in mouse hepatic microsomes and in man in vivo.

Pub. Date : 1987 Jul

PMID : 2891811






1 Functional Relationships(s)
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Protein Name
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1 CIM gave type II difference spectra with dissociation constants (Ks) of 10.4 and 111 microM while ROX gave reverse type I difference spectra with Ks of 55.6 microM. Potassium ribosomal oxygenase 2 Homo sapiens