Title : Flaxseed Oil Supplementation Improve Gene Expression Levels of PPAR-γ, LP(a), IL-1 and TNF-α in Type 2 Diabetic Patients with Coronary Heart Disease.

Pub. Date : 2017 Nov

PMID : 28916975






4 Functional Relationships(s)
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1 Flaxseed Oil Supplementation Improve Gene Expression Levels of PPAR-gamma, LP(a), IL-1 and TNF-alpha in Type 2 Diabetic Patients with Coronary Heart Disease. Linseed Oil tumor necrosis factor Homo sapiens
2 In addition, compared with the placebo, taking flaxseed oil supplements down-regulated gene expression levels of lipoprotein(a) [LP(a)] (P = 0.001), interleukin-1 (IL-1) (P = 0.001) and tumor necrosis factor alpha (TNF-alpha) (P = 0.02) in PBMC of diabetic patients with CHD. Linseed Oil tumor necrosis factor Homo sapiens
3 In addition, compared with the placebo, taking flaxseed oil supplements down-regulated gene expression levels of lipoprotein(a) [LP(a)] (P = 0.001), interleukin-1 (IL-1) (P = 0.001) and tumor necrosis factor alpha (TNF-alpha) (P = 0.02) in PBMC of diabetic patients with CHD. Linseed Oil tumor necrosis factor Homo sapiens
4 Overall, flaxseed oil supplementation for 12 weeks in diabetic patients with CHD significantly improved gene expression levels of PPAR-gamma, LP(a), IL-1 and TNF-alpha, but did not influence LDLR, IL-8 and TGF-beta. Linseed Oil tumor necrosis factor Homo sapiens