Pub. Date : 2017
PMID : 28915246
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tumor Necrosis Factor alpha (TNF-alpha) has been shown to be released by tumor cells in response to docetaxel, and lipopolysaccharides (LPS), the latter through activation of toll-like receptor 4 (TLR4). | Docetaxel | tumor necrosis factor | Homo sapiens |
| 2 | Tumor Necrosis Factor alpha (TNF-alpha) has been shown to be released by tumor cells in response to docetaxel, and lipopolysaccharides (LPS), the latter through activation of toll-like receptor 4 (TLR4). | Docetaxel | tumor necrosis factor | Homo sapiens |
| 3 | The acquisition of docetaxel resistance was accompanied by increased constitutive production of TNF-alphaand CXCL1, which waned at higher levels of resistance. | Docetaxel | tumor necrosis factor | Homo sapiens |
| 4 | In docetaxel-resistant MCF-7 and A2780 cell lines, the production of TNF-alpha could not be significantly augmented by docetaxel without the inhibition of P-gp, a transporter protein that promotes drug efflux from tumor cells. | Docetaxel | tumor necrosis factor | Homo sapiens |