Title : [Effect of hyperforin on learning and memory abilities and Aβ₁₋₄₂, βAPP and BACE1 protein expressions in hippocampus of Alzheimer's disease model mice].

Pub. Date : 2016 Aug

PMID : 28914032






1 Functional Relationships(s)
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1 Immunohistochemistry and western blot results showed thatas compared with the normal group, the Abeta1-42, betaAPP and BACE1 protein expression levels in hippocampus were significantly increased in mice of model group (P<0.01);as compared with the model group, Abeta1-42, betaAPP and BACE1 protein expression levels in hippocampus were decreased in mice of rosiglitazone group and HF high, middle and low dose groups (P<0.01 or P<0.05). Rosiglitazone beta-site APP cleaving enzyme 1 Mus musculus