Title : Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.

Pub. Date : 2017 Oct 10

PMID : 28904078






2 Functional Relationships(s)
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1 We also observed the formation of heteromeric complexes of CYP2D6 with CYP2E1 and CYP3A4, and found a significant modulation of these interactions by 3,4-methylenedioxymethylamphetamine, a widespread drug of abuse metabolized by CYP2D6. N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 We also observed the formation of heteromeric complexes of CYP2D6 with CYP2E1 and CYP3A4, and found a significant modulation of these interactions by 3,4-methylenedioxymethylamphetamine, a widespread drug of abuse metabolized by CYP2D6. N-Methyl-3,4-methylenedioxyamphetamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens