Title : Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy.

Pub. Date : 2017 Aug 15

PMID : 28903334






1 Functional Relationships(s)
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1 Imbalancing BER by overexpression of MPG, but not XRCC1, sensitises MMR-deficient colon cancer cells to 5-FU and TMZ and leads to ATP depletion and lactate accumulation. Temozolomide N-methylpurine DNA glycosylase Homo sapiens