Title : PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis.

Pub. Date : 2017

PMID : 28884018






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Moroever, Polo-like kinase 1-mediated phosphorylation of Cyk4/RACGAP1, a centralspindlin component at the midbody, facilitates binding of both RhoA guanine nucleotide exchange factor (epithelial cell transforming sequence 2 (Ect2)) and PP2A-B" that in turn dephosphorylates Cyk4 and disrupts Ect2 binding. Guanine Nucleotides epithelial cell transforming 2 Homo sapiens
2 Moroever, Polo-like kinase 1-mediated phosphorylation of Cyk4/RACGAP1, a centralspindlin component at the midbody, facilitates binding of both RhoA guanine nucleotide exchange factor (epithelial cell transforming sequence 2 (Ect2)) and PP2A-B" that in turn dephosphorylates Cyk4 and disrupts Ect2 binding. Guanine Nucleotides epithelial cell transforming 2 Homo sapiens
3 Moroever, Polo-like kinase 1-mediated phosphorylation of Cyk4/RACGAP1, a centralspindlin component at the midbody, facilitates binding of both RhoA guanine nucleotide exchange factor (epithelial cell transforming sequence 2 (Ect2)) and PP2A-B" that in turn dephosphorylates Cyk4 and disrupts Ect2 binding. Guanine Nucleotides epithelial cell transforming 2 Homo sapiens