Title : CD147 functions as the signaling receptor for extracellular divalent copper in hepatocellular carcinoma cells.

Pub. Date : 2017 Aug 1

PMID : 28881637






1 Functional Relationships(s)
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1 Cu2+-induced CD147 self-association also enhances the ability of HCC cells to stimulate MMP-2 expression from neighboring fibroblasts, as well as increases the invasiveness of HCC cells which is abolished by the copper chelator tetrathiomolybdate. tetrathiomolybdate basigin (Ok blood group) Homo sapiens