Title : HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders.

Pub. Date : 2017 Sep 4

PMID : 28871125






1 Functional Relationships(s)
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1 In C. elegans, capable of recognising toxic assemblies of amyloidogenic proteins, p17 induces a specific toxic effect which can be counteracted by tetracyclines, drugs able to hinder the formation of large oligomers and consequently amyloid fibrils. Tetracyclines family with sequence similarity 72 member B Homo sapiens