Title : Nup42 and IP6 coordinate Gle1 stimulation of Dbp5/DDX19B for mRNA export in yeast and human cells.

Pub. Date : 2017 Dec

PMID : 28869701






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Nup42 and IP6 coordinate Gle1 stimulation of Dbp5/DDX19B for mRNA export in yeast and human cells. Phytic Acid DEAD-box helicase 19B Homo sapiens
2 A nup42-CTD/gle1-CTD/Dbp5 trimeric complex forms in the presence of IP6 . Phytic Acid DEAD-box helicase 19B Homo sapiens
3 In vitro, Nup42-CTD and IP6 stimulate Gle1/hGle1B activation of Dbp5 and DDX19B recombinant proteins in similar, nonadditive manners, demonstrating complete functional conservation between humans and S. cerevisiae. Phytic Acid DEAD-box helicase 19B Homo sapiens
4 In vitro, Nup42-CTD and IP6 stimulate Gle1/hGle1B activation of Dbp5 and DDX19B recombinant proteins in similar, nonadditive manners, demonstrating complete functional conservation between humans and S. cerevisiae. Phytic Acid DEAD-box helicase 19B Homo sapiens