Title : Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents.

Pub. Date : 1987 Apr

PMID : 2885979






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Clofibrate, clofibric acid, fenofibric acid and dulofibrate, which are mainly hypotriglyceridaemic, increased the content in cytochromes P-450 (77-185% over control), and especially cytochrome P-452-dependent lauric acid 12-hydroxylation (5.6- to 8.4-fold increase). fenofibric acid cytochrome P450, family 4, subfamily a, polypeptide 1 Rattus norvegicus