Pub. Date : 2017 Aug 29
PMID : 28852062
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In mice pretreated with 6-ethyl-chenodeoxycholic acid (6-ECDCA), a selective FXR agonist, I/R induced changes were prevented and renal function and structure were improved. | obeticholic acid | nuclear receptor subfamily 1, group H, member 4 | Mus musculus |
| 2 | In mice pretreated with 6-ethyl-chenodeoxycholic acid (6-ECDCA), a selective FXR agonist, I/R induced changes were prevented and renal function and structure were improved. | obeticholic acid | nuclear receptor subfamily 1, group H, member 4 | Mus musculus |
| 3 | In further experiments administering 6-ECDCA to renal proximal tubular cells cultured under hypoxia, the renoprotective effects of FXR activation were associated with inhibition of oxidative and ER stress and with increased antioxidant activity. | obeticholic acid | nuclear receptor subfamily 1, group H, member 4 | Mus musculus |