Title : TGFβ1 Promotes Gemcitabine Resistance through Regulating the LncRNA-LET/NF90/miR-145 Signaling Axis in Bladder Cancer.

Pub. Date : 2017

PMID : 28839463






2 Functional Relationships(s)
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1 In this study, we found that during gemcitabine treatment lncRNA-Low Expression in Tumor (lncRNA-LET) was downregulated in chemoresistant UBC, accompanied with the enrichment of CSC population. gemcitabine ubiquitin C Homo sapiens
2 Collectively, we proved that the dysregulated lncRNA-LET/NF90/miR-145 axis by gemcitabine-induced TGFbeta1 promotes UBC chemoresistance through enhancing cancer cell stemness. gemcitabine ubiquitin C Homo sapiens