Pub. Date : 2018 Jan
PMID : 28833556
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This hypothesis predicts that isotretinoin (13-cis retinoic acid), the prodrug of all-trans retinoic acid (ATRA), exaggerates neural crest cell (NCC) apoptosis via upregulation of the pro-apoptotic transcription factor p53, the guardian of the genome. | Isotretinoin | tumor protein p53 | Danio rerio |
| 2 | This hypothesis predicts that isotretinoin (13-cis retinoic acid), the prodrug of all-trans retinoic acid (ATRA), exaggerates neural crest cell (NCC) apoptosis via upregulation of the pro-apoptotic transcription factor p53, the guardian of the genome. | Isotretinoin | tumor protein p53 | Danio rerio |
| 3 | Translational evidence implies that isotretinoin-stimulated overactivation of p53 during embryogenesis represents the molecular basis of isotretinoin"s teratogenicity. | Isotretinoin | tumor protein p53 | Danio rerio |
| 4 | Translational evidence implies that isotretinoin-stimulated overactivation of p53 during embryogenesis represents the molecular basis of isotretinoin"s teratogenicity. | Isotretinoin | tumor protein p53 | Danio rerio |