Title : Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision.

Pub. Date : 2017 Aug 21

PMID : 28827588






2 Functional Relationships(s)
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1 However, this result has been disputed, and it was suggested instead that NEIL1 is recruited by the monofunctional TDG for the 2"-deoxyribose excision step. Deoxyribose thymine DNA glycosylase Homo sapiens
2 We confirm direct NEIL1 TDG binding and NEIL1 mediated 2"-deoxyribose excision downstream of TDG glycosylase activity. Deoxyribose thymine DNA glycosylase Homo sapiens