Pub. Date : 2017 Oct
PMID : 28807874
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells. | Docosahexaenoic Acids | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | N-Acetyl-l-cysteine, a ROS scavenger, abrogated the DHA-induced increases in Akt phosphorylation, Nrf2 nuclear accumulation, and OSGIN1 expression. | Docosahexaenoic Acids | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, induction of OSGIN1 by DHA is at least partially associated with increased ROS production, which activates PI3K/Akt/Nrf2 signaling. | Docosahexaenoic Acids | AKT serine/threonine kinase 1 | Homo sapiens |