Pub. Date : 2000 Jun
PMID : 28796357
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CONCLUSIONS: Our data show that long-term tamoxifen treatment blocks the response of GH to exogenous GHRH and reduces IGF-1 levels, possibly by a central mechanism other than the demonstrated peripheral action. | Tamoxifen | insulin like growth factor 1 | Homo sapiens |
| 2 | The results of this study, keeping in mind the demonstrated mitogenic role of IGF-1 in cancer proliferation, can contribute to clarify the mechanism by which TAM exerts its antiproliferative effect. | Tamoxifen | insulin like growth factor 1 | Homo sapiens |