Title : Impaired CBS-H2S signaling axis contributes to MPTP-induced neurodegeneration in a mouse model of Parkinson's disease.

Pub. Date : 2018 Jan

PMID : 28774789






2 Functional Relationships(s)
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1 Furthermore, compared to rAAV-Vector, rAAV-Cbs injection reduced the aberrant accumulation of nitric oxide and 3-nitrotyrosine (an indicator of protein nitration) in the striatum of MPTP-treated mice. Nitric Oxide cystathionine beta-synthase Mus musculus
2 Moreover, glial CBS overexpression offered protection to midbrain dopaminergic neurons through repressing nitric oxide overproduction in both glial and neuronal cells induced by MPP+. Nitric Oxide cystathionine beta-synthase Mus musculus