Pub. Date : 2017
PMID : 28770024
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to assess in vitro the effects of metformin, phenformin, and metformin sulfenamide prodrugs on the activity of human AChE and butyrylcholinesterase (BuChE) and establish the type of inhibition. | Metformin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Metformin inhibited 50% of the AChE activity at micromolar concentrations (2.35 mumol/mL, mixed type of inhibition) and seemed to be selective towards AChE since it presented low anti-BuChE activity. | Metformin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | Metformin inhibited 50% of the AChE activity at micromolar concentrations (2.35 mumol/mL, mixed type of inhibition) and seemed to be selective towards AChE since it presented low anti-BuChE activity. | Metformin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |