Pub. Date : 2017 Sep 23
PMID : 28757412
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quercetin ameliorates learning and memory via the Nrf2-ARE signaling pathway in d-galactose-induced neurotoxicity in mice. | Quercetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | Quercetin also prevented changes in the neuronal cell morphology and apoptosis in the hippocampus as well as increased the expression of Nrf2, HO-1 and SOD in d-galactose-treated mice. | Quercetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 3 | Treatment with the Nrf2 inhibitor Brusatol reversed the effects of quercetin on HO-1 and SOD expression as well as neuronal cell protection. | Quercetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 4 | In conclusion, quercetin protected mice from d-galactose-induced cognitive functional impairment and neuronal cell apoptosis via activation of the Nrf2-ARE signaling pathway. | Quercetin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |