Title : Metformin Alleviated the Neuronal Oxidative Stress in Hippocampus of Rats under Single Prolonged Stress.

Pub. Date : 2017 Sep

PMID : 28752417






3 Functional Relationships(s)
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1 Metformin, the most commonly prescribed anti-diabetic drug, exerts its effects through 5"-adenosine monophosphate-activated protein kinase (AMPK) activation. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus
2 Metformin, the most commonly prescribed anti-diabetic drug, exerts its effects through 5"-adenosine monophosphate-activated protein kinase (AMPK) activation. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus
3 Metformin protected the hippocampus as evidenced by abolishing down-regulation of the AMPK pathway and up-regulating expression of oxidative stress-related genes. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus