Title : α-Geminal disubstituted pyrrolidine iminosugars and their C-4-fluoro analogues: Synthesis, glycosidase inhibition and molecular docking studies.

Pub. Date : 2017 Oct 1

PMID : 28751199






1 Functional Relationships(s)
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1 Appropriate manipulation of the anomeric carbon in the furanose fused pyrrolidine ring skeleton afforded alpha-geminal disubstituted pyrrolidine iminosugars 3a-c and C-4 fluoro derivatives 4a-c. Carbon complement C4A (Rodgers blood group) Homo sapiens