Title : Identification of interleukin-1 beta as a key mediator in the upregulation of Cav3.2-USP5 interactions in the pain pathway.

Pub. Date : 2017 Jan-Dec

PMID : 28741432






1 Functional Relationships(s)
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1 Moreover, disruption of the interaction between USP5 and Cav3.2 with TAT peptides suppressed acute nocifensive responses produced by interleukin-1 beta, which was similar to that achieved by elimination of T-type channel activity with the channel blockers, mibefradil, or TTA-A2. Mibefradil ubiquitin specific peptidase 5 (isopeptidase T) Mus musculus