Title : Cholinergic effects of histamine-H2 receptor antagonists partly through inhibition of acetylcholinesterase.

Pub. Date : 1986 Jun

PMID : 2874096






1 Functional Relationships(s)
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1 The potency of inhibitory activity of H2-antagonists on acetylcholinesterase estimated from median inhibitory dose were in the following order of decreasing activity: ranitidine greater than TZU-0460 greater than cimetidine greater than YM-11170, whereas that on pseudocholinesterase were TZU-0460 greater than ranitidine greater than cimetidine greater than YM-11170. Hydrogen acetylcholinesterase (Cartwright blood group) Homo sapiens