Title : Effect of sorafenib in a murine high risk penetrating keratoplasty model.

Pub. Date : 2017

PMID : 28730071






2 Functional Relationships(s)
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1 The sorafenib group showed reduced expression of VEGF-C, tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, VEGFR-2 and VEGFR-3 compared with DMSO group and PBS group (all P<0.05). Sorafenib kinase insert domain protein receptor Mus musculus
2 We suggest that a close linkage between decreased VEGF-C/VEGFR-2 and -3 signaling and increased corneal graft survival by sorafenib seems to exist. Sorafenib kinase insert domain protein receptor Mus musculus