Title : NF-κB-mediated inflammation correlates with calcium overload under arsenic trioxide-induced myocardial damage in Gallus gallus.

Pub. Date : 2017 Oct

PMID : 28728119






1 Functional Relationships(s)
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1 Moreover, As2O3 exposure significantly increased (P < 0.05) the mRNA levels of ITPR3, PMCA, TRPC1, TRPC3, STIM1, ORAI1 and pro-inflammatory genes, while the mRNA levels of ITPR1, ITPR2, RyR1, RyR3, SERCA, SLC8A1, CACNA1S and interleukin-10 were decreased (P < 0.05) by As2O3 exposure at 4, 8 and 12 weeks as compared with the corresponding control group. Arsenic Trioxide transient receptor potential cation channel subfamily C member 1 Gallus gallus