Title : An Amish founder mutation disrupts a PI(3)P-WHAMM-Arp2/3 complex-driven autophagosomal remodeling pathway.

Pub. Date : 2017 Sep 15

PMID : 28720660






2 Functional Relationships(s)
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1 An Amish founder mutation disrupts a PI(3)P-WHAMM-Arp2/3 complex-driven autophagosomal remodeling pathway. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) WASP homolog associated with actin, golgi membranes and microtubules Homo sapiens
2 Normal WHAMM function involved binding to the phospholipid PI(3)P and promoting actin nucleation at nascent autophagosomes. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) WASP homolog associated with actin, golgi membranes and microtubules Homo sapiens