Pub. Date : 2017 Oct 1
PMID : 28716527
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Consistently, BV6/Bortezomib co-treatment alone or in combination with zVAD.fmk increases phosphorylation of MLKL, a typical marker of necroptosis. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | mixed lineage kinase domain like pseudokinase | Homo sapiens |
| 2 | Similarly, pharmacological inhibitors of MLKL (i.e. NSA), RIP3 (i.e. GSK"872, Dabrafenib) or RIP1 (i.e. Necrostatin-1s) significantly rescue DG-75 cells from BV6/Bortezomib-induced cell death irrespective of the presence of zVAD.fmk. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | mixed lineage kinase domain like pseudokinase | Homo sapiens |