Title : Hepatitis B virus X protein activates E3 ubiquitin ligase Siah-1 to control virus propagation via a negative feedback loop.

Pub. Date : 2017 Jul

PMID : 28714848






1 Functional Relationships(s)
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Protein Name
Organism
1 For this effect, HBx sequentially activated ataxia telangiectasia mutated kinase and checkpoint kinase 2 via phosphorylation at the Ser-1981 and Thr-68 residues, respectively, which led to the activation of p53 via phosphorylation at the Ser-15 and Ser-20 residues. Threonine tumor protein p53 Homo sapiens