Pub. Date : 2017 Sep 9
PMID : 28712871
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Inhibitory experiments using a PI3K selective inhibitor, LY294002 or NVP-BEZ235, significantly enhanced the BITC-induced antiproliferation and apoptotic cell population with the attenuation of the BITC-induced activation of the PI3K/Akt/FoxO survival pathway. | benzyl isothiocyanate | AKT serine/threonine kinase 1 | Homo sapiens | ||
| 2 | Taken together, these results suggested that the PI3K/Akt/FoxO pathway negatively regulates the BITC-induced antiproliferation in human colorectal cancer cells. | benzyl isothiocyanate | AKT serine/threonine kinase 1 | Homo sapiens | ||