Title : Taxifolin reduces the cholesterol oxidation product-induced neuronal apoptosis by suppressing the Akt and NF-κB activation-mediated cell death.

Pub. Date : 2017 Sep

PMID : 28710022






1 Functional Relationships(s)
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1 Taxifolin, N-acetylcysteine, trolox, Akt inhibitor and Bay11-7085 attenuated the cholesterol oxidation product-induced changes in the apoptosis-related protein levels, activation of the Akt and NF-kappaB, reactive oxygen species production, GSH depletion and cell death. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid AKT serine/threonine kinase 1 Homo sapiens