Title : A system to identify inhibitors of mTOR signaling using high-resolution growth analysis in Saccharomyces cerevisiae.

Pub. Date : 2017 Aug

PMID : 28707282






1 Functional Relationships(s)
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1 Using this assay, we show that rapamycin derivatives behave similarly to rapamycin, while caffeine and the ATP competitive inhibitors Torin 1 and GSK2126458 are mTORC1 inhibitors in yeast that act independently of Fpr1. Adenosine Triphosphate CREB regulated transcription coactivator 1 Mus musculus