Pub. Date : 2017 Oct
PMID : 28702823
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Etoposide and doxorubicin enhance the sensitivity of triple negative breast cancers through modulation of TRAIL-DR5 axis. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
2 | In the TRAIL pre-treated cells, ET and DOX induced higher apoptosis, indicating their synergistic effect with TRAIL. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
3 | In the TRAIL pre-treated cells, ET and DOX induced higher apoptosis, indicating their synergistic effect with TRAIL. | Doxorubicin | TNF superfamily member 10 | Homo sapiens |
4 | The binding energy for TRAIL-DR5 complexation in the ternary complexes containing ET (-111.08 kcal/mol) and DOX (-76.35 kcal/mol) were higher than reported binding energy of binary complex (-53.70 kcal/mol). | Doxorubicin | TNF superfamily member 10 | Homo sapiens |