Title : Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection.

Pub. Date : 2017 Jul 11

PMID : 28698273






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase 1 (HMGCS1), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR [a rate-limiting step in the mevalonate pathway]), and farnesyl-diphosphate farnesyltransferase 1 (FDFT1 [a committed step in the cholesterol branch]) are repressed by multiple KSHV miRNAs. Cholesterol 3-hydroxy-3-methylglutaryl-CoA synthase 1 Homo sapiens