Pub. Date : 2017
PMID : 28686747
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development. | Cholesterol | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | Danio rerio |
| 2 | Our analysis confirmed that mutation of hmgcs1, which encodes the first enzyme in the cholesterol synthesis pathway, results in craniofacial abnormalities via defects in cranial neural crest cell differentiation. | Cholesterol | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | Danio rerio |