Title : MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma.

Pub. Date : 2017 Jul 7

PMID : 28686226






1 Functional Relationships(s)
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1 Both in vitro and in vivo, lipid-lowering alkaloid berberine (BBR) exhibited an anti-lymphoma activity through inhibiting MYC-driven downstream PCYT1A expression and inducing mitophagy-dependent necroptosis. Alkaloids MYC proto-oncogene, bHLH transcription factor Homo sapiens