Title : Zinc-finger protein 545 is inactivated due to promoter methylation and functions as a tumor suppressor through the Wnt/β-catenin, PI3K/AKT and MAPK/ERK signaling pathways in colorectal cancer.

Pub. Date : 2017 Sep

PMID : 28677721






1 Functional Relationships(s)
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1 The results showed that ZNF545 was expressed in adult normal colorectal tissues, but downregulated or silenced in CRC cell lines, and this mechanism was reversed by demethylation treatment with 5-aza-2"-deoxycytidine and trichostatin A. Decitabine zinc finger protein 82 Mus musculus