Title : Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice.

Pub. Date : 2017 Sep

PMID : 28668488






2 Functional Relationships(s)
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1 Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice. Glycyrrhetinic Acid high mobility group box 1 Mus musculus
2 These findings reflected that GA could alleviate APAP-induced hepatotoxicity, the possible mechanism is associated with down-regulation of CYP2E1 expression and deactivation of HMGB1-TLR4 signal pathway. Glycyrrhetinic Acid high mobility group box 1 Mus musculus