Title : Decreased Expression of Connexin 43 Blunts the Progression of Experimental GN.

Pub. Date : 2017 Oct

PMID : 28667079






2 Functional Relationships(s)
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1 Notably, 2 weeks after the induction of GN with nephrotoxic serum, mice with a heterozygous deletion of the connexin 43 gene (connexin 43+/-) had proteinuria, BUN, and serum creatinine levels significantly lower than those of wild-type animals. Creatinine gap junction protein, alpha 1 Mus musculus
2 Notably, 2 weeks after the induction of GN with nephrotoxic serum, mice with a heterozygous deletion of the connexin 43 gene (connexin 43+/-) had proteinuria, BUN, and serum creatinine levels significantly lower than those of wild-type animals. Creatinine gap junction protein, alpha 1 Mus musculus