Pub. Date : 2017 Dec
PMID : 28660384
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hepatic ATP-binding cassette A1 (ABCA1) transporter is the modulator of intrahepatic cholesterol levels via the efflux of cholesterol into plasma. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
2 | Hepatic ATP-binding cassette A1 (ABCA1) transporter is the modulator of intrahepatic cholesterol levels via the efflux of cholesterol into plasma. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
3 | Hepatic ATP-binding cassette A1 (ABCA1) transporter is the modulator of intrahepatic cholesterol levels via the efflux of cholesterol into plasma. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
4 | Hepatic ATP-binding cassette A1 (ABCA1) transporter is the modulator of intrahepatic cholesterol levels via the efflux of cholesterol into plasma. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
5 | A cholesterol efflux study was conducted with Abca1 knock down using siRNA in WIF9 cells. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
6 | Cholesterol levels in the ABCA1 siRNA cells in the medium were significantly decreased compared with those in controls (P < 0.05). | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
7 | Upregulated hepatic ABCA1 may lead to efflux of cholesterol into plasma, thus explaining the mechanism of cholestasis leading to hypercholesterolemia. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |