Title : Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-α secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytes.

Pub. Date : 2017

PMID : 28659738






1 Functional Relationships(s)
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1 Results: During the preadipocyte differentiation process, RA suppressed peroxisome proliferator-activated receptor-gamma and CCAAT/enhancer binding protein-alpha, and activated p-ERK1/2 and p-Smad3; inhibition of adipogenesis by RA was partially restored following treatment with p-ERK1/2 and p-Smad3 inhibitors. rosmarinic acid CCAAT enhancer binding protein alpha Homo sapiens