Title : Erythropoietin ameliorates PA-induced insulin resistance through the IRS/AKT/FOXO1 and GSK-3β signaling pathway, and inhibits the inflammatory response in HepG2 cells.

Pub. Date : 2017 Aug

PMID : 28656239






1 Functional Relationships(s)
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1 The specific PI3K inhibitors, LY294002 and wortmannin, markedly inhibited the EPO-mediated increases in p-AKT (Ser473), p-FOXO1 (Ser256) and p-GSK-3beta (Ser9) in the PA-induced HepG2 cells (P<0.05). Wortmannin AKT serine/threonine kinase 1 Homo sapiens