Pub. Date : 2017 Aug 11
PMID : 28655775
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 2 | Recently, we demonstrated that the iron chaperone poly(rC)-binding protein 2 (PCBP2) can directly receive ferrous iron from DMT1 or transfer iron to the iron exporter, ferroportin 1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 3 | Recently, we demonstrated that the iron chaperone poly(rC)-binding protein 2 (PCBP2) can directly receive ferrous iron from DMT1 or transfer iron to the iron exporter, ferroportin 1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 4 | Recently, we demonstrated that the iron chaperone poly(rC)-binding protein 2 (PCBP2) can directly receive ferrous iron from DMT1 or transfer iron to the iron exporter, ferroportin 1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 5 | Recently, we demonstrated that the iron chaperone poly(rC)-binding protein 2 (PCBP2) can directly receive ferrous iron from DMT1 or transfer iron to the iron exporter, ferroportin 1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 6 | Recently, we demonstrated that the iron chaperone poly(rC)-binding protein 2 (PCBP2) can directly receive ferrous iron from DMT1 or transfer iron to the iron exporter, ferroportin 1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 7 | Recently, we demonstrated that the iron chaperone poly(rC)-binding protein 2 (PCBP2) can directly receive ferrous iron from DMT1 or transfer iron to the iron exporter, ferroportin 1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 8 | Furthermore, in vitro reconstitution experiments with purified recombinant proteins indicated that HO1 could bind to PCBP2 in the presence of heme, whereas loading of PCBP2 with ferrous iron caused PCBP2 to lose its affinity for HO1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 9 | Furthermore, in vitro reconstitution experiments with purified recombinant proteins indicated that HO1 could bind to PCBP2 in the presence of heme, whereas loading of PCBP2 with ferrous iron caused PCBP2 to lose its affinity for HO1. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 10 | These results indicate that ferrous iron released from heme can be bound by PCBP2 and suggest a model for an integrated heme catabolism and iron transport metabolon. | Iron | poly(rC) binding protein 2 | Homo sapiens |
| 11 | These results indicate that ferrous iron released from heme can be bound by PCBP2 and suggest a model for an integrated heme catabolism and iron transport metabolon. | Iron | poly(rC) binding protein 2 | Homo sapiens |