Title : Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo.

Pub. Date : 2018 Jan

PMID : 28649853






1 Functional Relationships(s)
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1 Small-molecule analogues of second mitochondria-derived activator of caspase (SMAC) mimetic in association with mixed lineage kinase domain-like protein (MLKL)-pDNA and z-VAD-fmk have shown ideal antitumor effects in colon cancer cells in vitro via induction of RIP3-dependent necroptosis. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone receptor-interacting serine-threonine kinase 3 Mus musculus