Title : UCA1 involved in the metformin-regulated bladder cancer cell proliferation and glycolysis.

Pub. Date : 2017 Jun

PMID : 28641488






2 Functional Relationships(s)
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1 Metformin downregulated both endogenous and exogenous UCA1 expression, leading to the inhibition of mammalian target of rapamycin-signal transducer and activator of transcription 3-hexokinase 2 signaling pathway. Metformin urothelial cancer associated 1 Homo sapiens
2 Our study provided the first evidence that metformin inhibited proliferation and glycolysis in cancer cells through regulation of long non-coding RNA UCA1. Metformin urothelial cancer associated 1 Homo sapiens