Title : miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer.

Pub. Date : 2017 Jun 21

PMID : 28638102






1 Functional Relationships(s)
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1 Herein, we demonstrated that overexpression of miR-509-5p and miR-1243 increased the expression of E-cadherin through the suppression of EMT-related gene expression and that drug sensitivity increased with a combination of each of these miRNAs and gemcitabine. gemcitabine cadherin 1 Homo sapiens