Pub. Date : 2017 Jun 15
PMID : 28622511
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we demonstrate that induction of the iron-sequestering ferritin H chain (FTH) in response to polymicrobial infections is critical to establish disease tolerance to sepsis. | Iron | ferritin heavy chain 1 | Homo sapiens |
| 2 | Here, we demonstrate that induction of the iron-sequestering ferritin H chain (FTH) in response to polymicrobial infections is critical to establish disease tolerance to sepsis. | Iron | ferritin heavy chain 1 | Homo sapiens |
| 3 | The protective effect of FTH is exerted via a mechanism that counters iron-driven oxidative inhibition of the liver glucose-6-phosphatase (G6Pase), and in doing so, sustains endogenous glucose production via liver gluconeogenesis. | Iron | ferritin heavy chain 1 | Homo sapiens |