Pub. Date : 2017 Jun 12
PMID : 28607419
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The study allows the thorough analysis of the opening events at the atomic scale: i) ATP hydrolysis at the Smc1A site, evaluating the role of the carboxy-terminal domain of Rad21 in the process; ii) the activation of the Smc3 site potentially mediated by the movement of specific amino acids; and iii) opening of the head domains after the two ATP hydrolysis events. | Adenosine Triphosphate | structural maintenance of chromosomes 3 | Homo sapiens |
2 | Our study suggests that the cohesin ring opening is triggered by a sequential activation of the ATP sites in which ATP hydrolysis at the Smc1A site induces ATPase activity at the Smc3 site. | Adenosine Triphosphate | structural maintenance of chromosomes 3 | Homo sapiens |
3 | Our study suggests that the cohesin ring opening is triggered by a sequential activation of the ATP sites in which ATP hydrolysis at the Smc1A site induces ATPase activity at the Smc3 site. | Adenosine Triphosphate | structural maintenance of chromosomes 3 | Homo sapiens |