Pub. Date : 2017 Jul
PMID : 28604676
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A high concentration of cholesterol and fatty acid, however, induced cellular reactive oxygen species (ROS) that oxidized Cys277, resulting in ACAT2 stabilization and subsequently elevated cholesteryl esters. | Reactive Oxygen Species | acetyl-Coenzyme A acetyltransferase 2 | Mus musculus |
| 2 | A high concentration of cholesterol and fatty acid, however, induced cellular reactive oxygen species (ROS) that oxidized Cys277, resulting in ACAT2 stabilization and subsequently elevated cholesteryl esters. | Reactive Oxygen Species | acetyl-Coenzyme A acetyltransferase 2 | Mus musculus |
| 3 | This unconventional cysteine ubiquitylation of ACAT2 constitutes an important mechanism for sensing lipid-overload-induced ROS and fine-tuning lipid homeostasis. | Reactive Oxygen Species | acetyl-Coenzyme A acetyltransferase 2 | Mus musculus |